Improving influenza vaccination in chronically ill children using a tertiary-care based vaccination clinic: Is there a role for the live-attenuated influenza vaccine (LAIV)?
Identifieur interne : 000145 ( Main/Exploration ); précédent : 000144; suivant : 000146Improving influenza vaccination in chronically ill children using a tertiary-care based vaccination clinic: Is there a role for the live-attenuated influenza vaccine (LAIV)?
Auteurs : Joanna Merckx [Canada] ; Deirdre Mccormack [Canada] ; Caroline Quach [Canada]Source :
- Vaccine [ 1873-2518 ] ; 2016.
Descripteurs français
- KwdFr :
- MESH :
- usage thérapeutique : Vaccins antigrippaux, Vaccins atténués.
- Adolescent, Canada, Centres de soins tertiaires, Enfant, Enfant d'âge préscolaire, Grippe humaine, Humains, Maladie chronique, Nourrisson, Vaccination, Études transversales.
English descriptors
- KwdEn :
- Adolescent, Canada, Child, Child, Preschool, Chronic Disease, Contraindications, Cross-Sectional Studies, Humans, Infant, Influenza Vaccines (therapeutic use), Influenza, Human (prevention & control), Tertiary Care Centers, Vaccination (statistics & numerical data), Vaccines, Attenuated (therapeutic use).
- MESH :
- chemical , therapeutic use : Influenza Vaccines, Vaccines, Attenuated.
- prevention & control : Influenza, Human.
- statistics & numerical data : Vaccination.
- Adolescent, Canada, Child, Child, Preschool, Chronic Disease, Contraindications, Cross-Sectional Studies, Humans, Infant, Tertiary Care Centers.
Abstract
BACKGROUND
Children with underlying medical conditions should receive influenza vaccine (IV) yearly; yet this remains sub-optimal. We aimed to describe our experience with a tertiary-care hospital-based influenza vaccination clinic for this at-risk population.
METHODS
From October to December 2012, 2013, and 2014, we ran an influenza vaccination clinic at the Montreal Children's Hospital, where children with high-risk conditions come for their follow-up. Both injectable IV (IIV) and live-attenuated IV (LAIV) were offered free of charge to patients and their household contacts. Upon vaccination, parents were asked to fill a pre-piloted questionnaire.
RESULTS
We vaccinated a total of 2640 high-risk children and 1912 household members during the three influenza vaccination seasons. In 2012 and 2013, 631 and 630 patients with chronic illnesses were vaccinated, compared to 1379 in 2014. Caregivers preferred LAIV primarily because no needle was involved (49.0%) and because it was perceived as less painful (46.9%). LAIV was administered to 69% (2012), 55% (2013) and 47% (2014) of high-risk children. The main reason for not receiving LAIV was because it was contra-indicated. A small fraction of children previously vaccinated with LAIV who did not present any contraindication to LAIV opted for IIV: 12/101 (11.8%) in 2013 and 16/272 (5.9%) in 2014. In 2014, this was mainly due to a previous negative experience with LAIV (11/16).
CONCLUSION
Having an influenza vaccination clinic on site at a tertiary care hospital, where children come for their scheduled visits, facilitates yearly influenza vaccination in children with chronic illnesses. LAIV is preferred by caregivers and patients, when not contraindicated.
DOI: 10.1016/j.vaccine.2015.12.055
PubMed: 26752064
Affiliations:
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Electronic address: caroline.quach@mcgill.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>McGill University Department of Epidemiology, Statistics and Occupational Health, Montreal, QC, Canada; Division of Infectious Diseases, Department of Pediatrics, The Montreal Children's Hospital, Montreal, QC, Canada; Vaccine Study Centre, Research Institute of the McGill University Health Centre, Montreal, QC</wicri:regionArea><wicri:noRegion>QC</wicri:noRegion></affiliation></author></analytic><series><title level="j">Vaccine</title><idno type="eISSN">1873-2518</idno><imprint><date when="2016" type="published">2016</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent</term><term>Canada</term><term>Child</term><term>Child, Preschool</term><term>Chronic Disease</term><term>Contraindications</term><term>Cross-Sectional Studies</term><term>Humans</term><term>Infant</term><term>Influenza Vaccines (therapeutic use)</term><term>Influenza, Human (prevention & control)</term><term>Tertiary Care Centers</term><term>Vaccination (statistics & numerical data)</term><term>Vaccines, Attenuated (therapeutic use)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent</term><term>Canada</term><term>Centres de soins tertiaires</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Grippe humaine ()</term><term>Humains</term><term>Maladie chronique</term><term>Nourrisson</term><term>Vaccination ()</term><term>Vaccins antigrippaux (usage thérapeutique)</term><term>Vaccins atténués (usage thérapeutique)</term><term>Études transversales</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Influenza Vaccines</term><term>Vaccines, Attenuated</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Influenza, Human</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Vaccination</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Vaccins antigrippaux</term><term>Vaccins atténués</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Canada</term><term>Child</term><term>Child, Preschool</term><term>Chronic Disease</term><term>Contraindications</term><term>Cross-Sectional Studies</term><term>Humans</term><term>Infant</term><term>Tertiary Care Centers</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Canada</term><term>Centres de soins tertiaires</term><term>Enfant</term><term>Enfant d'âge préscolaire</term><term>Grippe humaine</term><term>Humains</term><term>Maladie chronique</term><term>Nourrisson</term><term>Vaccination</term><term>Études transversales</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b></p><p>Children with underlying medical conditions should receive influenza vaccine (IV) yearly; yet this remains sub-optimal. We aimed to describe our experience with a tertiary-care hospital-based influenza vaccination clinic for this at-risk population.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>From October to December 2012, 2013, and 2014, we ran an influenza vaccination clinic at the Montreal Children's Hospital, where children with high-risk conditions come for their follow-up. Both injectable IV (IIV) and live-attenuated IV (LAIV) were offered free of charge to patients and their household contacts. Upon vaccination, parents were asked to fill a pre-piloted questionnaire.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>We vaccinated a total of 2640 high-risk children and 1912 household members during the three influenza vaccination seasons. In 2012 and 2013, 631 and 630 patients with chronic illnesses were vaccinated, compared to 1379 in 2014. Caregivers preferred LAIV primarily because no needle was involved (49.0%) and because it was perceived as less painful (46.9%). LAIV was administered to 69% (2012), 55% (2013) and 47% (2014) of high-risk children. The main reason for not receiving LAIV was because it was contra-indicated. A small fraction of children previously vaccinated with LAIV who did not present any contraindication to LAIV opted for IIV: 12/101 (11.8%) in 2013 and 16/272 (5.9%) in 2014. In 2014, this was mainly due to a previous negative experience with LAIV (11/16).</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>Having an influenza vaccination clinic on site at a tertiary care hospital, where children come for their scheduled visits, facilitates yearly influenza vaccination in children with chronic illnesses. LAIV is preferred by caregivers and patients, when not contraindicated.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26752064</PMID><DateCompleted><Year>2016</Year><Month>09</Month><Day>29</Day></DateCompleted><DateRevised><Year>2017</Year><Month>11</Month><Day>16</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1873-2518</ISSN><JournalIssue CitedMedium="Internet"><Volume>34</Volume><Issue>6</Issue><PubDate><Year>2016</Year><Month>Feb</Month><Day>03</Day></PubDate></JournalIssue><Title>Vaccine</Title><ISOAbbreviation>Vaccine</ISOAbbreviation></Journal><ArticleTitle>Improving influenza vaccination in chronically ill children using a tertiary-care based vaccination clinic: Is there a role for the live-attenuated influenza vaccine (LAIV)?</ArticleTitle><Pagination><MedlinePgn>750-6</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.vaccine.2015.12.055</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0264-410X(15)01866-6</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Children with underlying medical conditions should receive influenza vaccine (IV) yearly; yet this remains sub-optimal. We aimed to describe our experience with a tertiary-care hospital-based influenza vaccination clinic for this at-risk population.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">From October to December 2012, 2013, and 2014, we ran an influenza vaccination clinic at the Montreal Children's Hospital, where children with high-risk conditions come for their follow-up. Both injectable IV (IIV) and live-attenuated IV (LAIV) were offered free of charge to patients and their household contacts. Upon vaccination, parents were asked to fill a pre-piloted questionnaire.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">We vaccinated a total of 2640 high-risk children and 1912 household members during the three influenza vaccination seasons. In 2012 and 2013, 631 and 630 patients with chronic illnesses were vaccinated, compared to 1379 in 2014. Caregivers preferred LAIV primarily because no needle was involved (49.0%) and because it was perceived as less painful (46.9%). LAIV was administered to 69% (2012), 55% (2013) and 47% (2014) of high-risk children. The main reason for not receiving LAIV was because it was contra-indicated. A small fraction of children previously vaccinated with LAIV who did not present any contraindication to LAIV opted for IIV: 12/101 (11.8%) in 2013 and 16/272 (5.9%) in 2014. In 2014, this was mainly due to a previous negative experience with LAIV (11/16).</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Having an influenza vaccination clinic on site at a tertiary care hospital, where children come for their scheduled visits, facilitates yearly influenza vaccination in children with chronic illnesses. LAIV is preferred by caregivers and patients, when not contraindicated.</AbstractText><CopyrightInformation>Copyright © 2016 Elsevier Ltd. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Merckx</LastName><ForeName>Joanna</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>McGill University Department of Epidemiology, Statistics and Occupational Health, Montreal, QC, Canada; Division of Infectious Diseases, Department of Pediatrics, The Montreal Children's Hospital, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>McCormack</LastName><ForeName>Deirdre</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Vaccine Study Centre, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Quach</LastName><ForeName>Caroline</ForeName><Initials>C</Initials><AffiliationInfo><Affiliation>McGill University Department of Epidemiology, Statistics and Occupational Health, Montreal, QC, Canada; Division of Infectious Diseases, Department of Pediatrics, The Montreal Children's Hospital, Montreal, QC, Canada; Vaccine Study Centre, Research Institute of the McGill University Health Centre, Montreal, QC, Canada. 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